Anagrams of: UPWO_

• a common venereal disease caused by the treponema pallidum spirochete; symptoms change through progressive stages; can be congenital (transmitted through the placenta)

• a contagious disease characterized by purulent skin eruptions that may leave pock marks

• strike hard

• hit hard

• To beat, to strike.

• To defeat thoroughly.

• pan with a convex bottom; used for frying in Chinese cooking

• The means by which something is accomplished.

• An artificial barrow or tumulus.

• A small hill in northern England. (Usage preserved mainly in place names.)

• To what degree.

• In what manner.

• In what state.

• Used as a modifier to indicate surprise, delight, or other strong feelings in an exclamation.

• The manner or way that.

• That, the fact that, the way that.

• A greeting, used in representations of Native American speech.

• a United Nations agency to coordinate international health activities and to help governments improve health services

• a joke that seems extremely funny

• impress greatly

• Darling, sweetheart.