8-Letter Words Containing: P,O,E,M

• a tranquilizing drug (trade name Serax) used to treat anxiety and insomnia and alcohol withdrawal

• make optimal; get the most out of; use best

• modify to achieve maximum efficiency in storage capacity or time or cost

• act as an optimist and take a sunny view of the world

• engage in a controversy

• An underground room or cavern (also used figuratively).

• A combination of diced onions, carrots, celery and herbs sautéed in oil or butter as used in French cooking.

• A mixture.