Anagrams of AYWIRE

• physically and mentally fatigued

• exhaust or get tired through overuse or great strain or stress

• lose interest or become bored with something or somebody

• marked by keen caution and watchful prudence

• openly distrustful and unwilling to confide

• away from the correct or expected course

• turned or twisted to one side

• turned or twisted toward one side

• not functioning properly

• of or relating to wire

• lean and sinewy

• of hair that resembles wire in stiffness

• how something is done or how it happens

• to have the ability to produce a particular effect or achieve an end

• a line leading to a place or point

• the condition of things generally

• a course of conduct

• any artifact consisting of a road or path affording passage from one place to another

• a journey or passage

• space for movement

• the property of distance in general

• doing as one pleases or chooses

• a general category of things; used in the expression `in the way of'

• a portion of something divided into shares

• to a great degree or by a great distance; very much (`right smart' is regional in the United States)

• wood of a yew; especially the durable fine-grained light brown or red wood of the English yew valued for cabinetwork and archery bows

• any of numerous evergreen trees or shrubs having red cup-shaped berries and flattened needlelike leaves

• humorously sarcastic or mocking

• bent to one side

• an erratic deflection from an intended course

• be wide open

• deviate erratically from a set course

• swerve off course momentarily

• the 25th letter of the Roman alphabet

• a period of time containing 365 (or 366) days

• a period of time occupying a regular part of a calendar year that is used for some particular activity

• the period of time that it takes for a planet (as, e.g., Earth or Mars) to make a complete revolution around the sun

• a body of students who graduate together