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We've checked our database and believe the answer is INAPICKLE which was last seen in the The Guardian Cryptic crossword.
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We think the answer to this crossword clue is: INAPICKLE

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LettersAnswerClue
99%9INAPICKLEExact Match!
No meanings yet for this word...
40%5 Common treatment for anxiety and panic disorders
noun

• an antianxiety agent (trade name Xanax) of the benzodiazepine class

35%10 Deeply troubled or troubled
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The Guardian Cryptic28 Dec 2017 Across 27 INAPICKLE
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