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Irritation Suffix

We've checked our database and believe the answer is ITIS which was last seen in the New York Times NYT crossword.
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We think the answer to this crossword clue is: ITIS

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99%4ITISExact Match!
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17%5 Causes irritation
verb

• cause annoyance in; disturb, especially by minor irritations

• make turbid by stirring up the sediments of

17%5 Moods of irritation
noun

• a state of agitated irritation

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Clue Last Found In...

Source #Number Answer
New York Times19 Sep 2008 Across 22 ITIS
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