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Blood Factor One Noted For Considerable Flow

We've checked our database and believe the answer is RHONE which was last seen in the The Guardian Cryptic crossword.
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We think the answer to this crossword clue is: RHONE

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99%5Exact Match!
noun

• a major French river; flows into the Mediterranean near Marseilles

28%9 This blood-clotting factor is also known as Hageman factor.
noun

• coagulation factor whose deficiency results in prolongation of clotting time of venous blood

26%6 Asian monkey - blood factor
noun

• of southern Asia; used in medical research

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The Guardian Cryptic10 Sep 2010 Across 27
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This blood-clotting factor is also known as Hageman factor.

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