SUBSTANCE

The real physical matter of which a person or thing consists

Example: "Dna is the substance of our genes"

The choicest or most essential or most vital part of some idea or experience

Example: "The gist of the prosecutor's argument"

The idea that is intended

Example: "What is the meaning of this proverb?"

Material of a particular kind or constitution

Example: "The immune response recognizes invading substances"

Considerable capital (wealth or income)

Example: "He is a man of means"

Content communicating a message; what something is about

The property of holding together and retaining its shape

Example: "Wool has more body than rayon"

A particular kind or species of matter with uniform properties

Example: "Shigella is one of the most toxic substances known to man"